Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1

Details Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4015 (2006.01) A61K 31/4025 (2006.01) A61P 3/10 (2006.01) C07D 207/26 (2006.01)

Patent

CA 2648236

The present invention discloses novel compounds of Formula I: having 11 Beta-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11Beta-HSD type 1 activity. X-17377

La présente invention se rapporte à de nouveaux composés représentés par la formule (I), qui présentent une activité antagoniste contre la 11.beta.-HSD de type 1, ainsi qu'à des procédés de préparation de tels composés. Dans un autre mode de réalisation, l'invention concerne des compositions pharmaceutiques contenant des composés représentés par la formule (I), ainsi que des procédés d'utilisation desdits composés et compositions pour traiter le diabète, l'hyperglycémie, l'obésité, l'hypertension, l'hyperlipidémie, le syndrome métabolique et d'autres maladies associées à l'activité de la 11.beta.-HSD de type 1.

Affiliated with

Also associated with

Rating

Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1988962