Inhibitors of 11.beta.-hydroxysteroid dehydrogenase type 1

Details Inhibitors of 11.beta.-hydroxysteroid dehydrogenase type 1 Inhibitors of 11.beta.-hydroxysteroid dehydrogenase type 1

C - Chemistry, Metallurgy

07

D

C07D 221/20 (2006.01) A61K 31/438 (2006.01) A61P 3/00 (2006.01) C07D 471/10 (2006.01)

Patent

CA 2716128

This invention relates to novel compounds of the Formulae I or II and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11 .beta.-HSD 1 in mammals. Formula (I).

Cette invention porte sur de nouveaux composés représentés par les Formules I ou II et sur leurs sels pharmaceutiquement acceptables, et sur des compositions pharmaceutiques de ceux-ci qui sont utiles pour le traitement thérapeutique de maladies associées à la modulation ou à l'inhibition de la 11ß-HSD 1 chez les mammifères.

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