Inhibitors of akt activity

Details Inhibitors of akt activity Inhibitors of akt activity

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61P 35/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2602197

The instant invention provides for compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.

L'invention concerne des composés qui inhibent l'activité Akt. En particulier, les composés décrits inhibent sélectivement un ou deux des isoformes Akt. L'invention concerne également des compositions comprenant de tels composés inhibiteurs, ainsi que des procédés d'inhibition de l'activité Akt par administration du composé à un patient nécessitant un traitement anticancéreux.

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