Inhibitors of aminoglycoside nephrotoxicity

A - Human Necessities – 61 – K

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167/202, 167/206

A61K 31/78 (2006.01) A61K 31/795 (2006.01)

Patent

CA 2012459

Abstract The use of water-soluble polyanionic organic acid polymers in the weight range of from about 1,000 to 30,000 daltons to inhibit aminoglycoside nephrotoxicity. These polyanionic polymers are homopolymers or copolymers comprised of monomers selected from acrylic, methacryclic, vinylsulfonic and maleic acids; and are in a pharmaceutically acceptable salt form.

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