Inhibitors of angiopoietin-like 4 protein, combinations, and...

Details Inhibitors of angiopoietin-like 4 protein, combinations, and... Inhibitors of angiopoietin-like 4 protein, combinations, and...

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01)

Patent

CA 2574758

Modulators of angiopoietin-like 4 protein are provided along with methods for their use in the treatment of diseases and pathological conditions. Combinations of ANGPTL4 antagonists and other therapeutics, e.g., anti-cancer agents, and methods of their use in the treatment of mammals susceptible to or diagnosed with cancer, or with relapse tumor growth or relapse cancer cell growth are also provided.

L'invention concerne des modulateurs de la protéine 4 de type angiopoïétine ainsi que leurs méthodes d'utilisation dans le traitement de maladies et d'états pathologiques. Elle concerne également des combinaisons d'antagonistes d'ANGPTL4 et d'autres agents thérapeutiques, tels que des agents anticancéreux, ainsi que leurs méthodes d'utilisation dans le traitement de mammifères présentant ou risquant de développer un cancer, une croissance tumorale récidivante ou une croissance de cellules cancéreuses récidivante.

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