Inhibitors of bacterial nad synthetase

Details Inhibitors of bacterial nad synthetase Inhibitors of bacterial nad synthetase

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A01N 43/38 (2006.01) A61K 31/40 (2006.01) C07C 229/42 (2006.01) C07C 235/46 (2006.01) C07C 235/64 (2006.01) C07D 209/08 (2006.01) C07D 209/12 (2006.01) C07D 209/42 (2006.01) C07D 213/80 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2341506

The present invention provides methods of synthesizing and screening inhibitors of bacterial NAD synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial NAD synthetase enzyme.

Cette invention se rapporte à des procédés servant à la synthèse et au criblage d'agents inhibiteurs de l'enzyme NAD (nicotinamide-adénine-dinucléotide)-synthétase bactérienne, à des composés de ces agents, ainsi qu'à des procédés servant au traitement des infections bactériennes et microbiennes à l'aide d'agents inhibiteurs de l'enzyme NAD-synthétase bactérienne.

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