Inhibitors of .beta.-amyloid protein production

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/06 (2006.01) A61K 31/16 (2006.01) A61K 31/27 (2006.01) A61K 31/535 (2006.01) A61K 31/69 (2006.01) A61K 31/695 (2006.01) A61K 38/05 (2006.01) C07C 237/22 (2006.01) C07C 271/20 (2006.01) C07C 271/22 (2006.01) C07C 279/18 (2006.01) C07D 295/205 (2006.01) C07D 295/215 (2006.01) C07F 5/02 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2171882

This invention relates to compounds and pharmaceutical compositions, and methods for inhibiting or preventing the amyloid protein deposits in the brain which are associated with Alzheimer's disease and aged Down's syndrome patients. More particularly, it relates to the treatment of Alzheimer's disease.

L'invention concerne des composés et des compositions pharmaceutiques, ainsi que des procédés d'inhibition ou de prévention des dépôts de protéines d'amyloïde dans le cerveau qui sont associés à la maladie d'Alzheimer et au syndrome de Down chez les patients âgés. L'invention porte, plus particulièrement, sur le traitement de la maladie d'Alzheimer.

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