Inhibitors of c-fms kinase

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 405/14 (2006.01) A61K 31/4178 (2006.01) A61K 31/4439 (2006.01) A61K 31/46 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 451/06 (2006.01) C07D 493/08 (2006.01) C07D 493/18 (2006.01)

Patent

CA 2702898

The invention is directed to compounds of Formula I wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c- fms kinase.

L'invention porte sur des composés représentés par la formule I, dans laquelle Z, X, J, R2 et W sont indiqués dans la description, ainsi que sur des solvates, des hydrates, des tautomère et des sels pharmaceutiquement acceptables de ceux-ci, qui inhibent des protéines tyrosine kinases, en particulier la c-fms kinase.

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