Inhibitors of carbonic anhydrase ix

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/18 (2006.01) A61K 31/4192 (2006.01) A61K 31/444 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2711678

Novel radiopharmaceuticals that are useful in diag-nostic imaging and therapeutic treatment of disease characterized by over expression of CA-IX comprise a complex that contains a sulfonamide moiety which Ls capable of binding the active catalyt-ic site of CA- IX, and a radionuclide adapted for radioimaging and/ or radiotherapy:

L'invention concerne de nouveaux produits radiopharmaceutiques qui sont utiles dans l'imagerie diagnostique et le traitement thérapeutique d'une maladie caractérisée par la surexpression de la CA-IX et qui comprennent un complexe qui contient un fragment de sulfonamide qui peut se lier au site catalytique actif de CA-IX, ainsi qu'un radionucléide adapté pour la radio-imagerie et/ou la radiothérapie.

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