Inhibitors of checkpoint kinases

Details Inhibitors of checkpoint kinases Inhibitors of checkpoint kinases

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2589893

The instant invention provides for compounds which comprise fused pyrazoles that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.

L'invention concerne des composés comprenant des pyrazoles fusionnées inhibant l'activité de la CHK1. L'invention concerne également des compositions contenant ces composés inhibiteurs, ainsi que des méthodes d'inhibition de l'activité de la CHK1 consistant à administrer ledit composé à un patient nécessitant un traitement contre le cancer.

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