C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/06 (2006.01) C07D 205/04 (2006.01) C07D 207/04 (2006.01) C07D 207/16 (2006.01) C07D 207/20 (2006.01) C07D 207/22 (2006.01) C07D 209/42 (2006.01) C07D 209/46 (2006.01) C07D 209/48 (2006.01) C07D 217/14 (2006.01) C07D 217/16 (2006.01) C07D 217/26 (2006.01) C07D 263/06 (2006.01) C07D 277/04 (2006.01) C07D 277/06 (2006.01) C07D 295/125 (2006.01) C07D 295/185 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 409/06 (2006.01) C07D 417/06 (2006.01) C07K 5/078 (2006.01) C07K
Patent
CA 2471204
Novel inhibitors of dipeptidyl peptidase IV (DPP IV), pharmaceutical compositions comprising therapeutically effective amounts of novel inhibitors of DPP IV, and novel methods of treating medical conditions are provided. The novel inhibitors of DPP IV described herein are useful in the treatment of neurological disorders, diabetes, inflammatory disorders such as arthritis, obesity, osteoporosis, and of such other enumerated conditions as can be treated with inhibitors of DPP IV.
La présente invention concerne de nouveaux inhibiteurs de la dipeptidyl peptidase IV (DPP IV), des compositions pharmaceutiques renfermant des quantités thérapeutiquement efficaces des nouveaux inhibiteurs de DPP IV, ainsi que de nouvelles méthodes de traitement des pathologies médicales. Les nouveaux inhibiteurs de DPP IV présentés dans cette invention sont utiles dans le traitement des troubles neurologiques, du diabète, des troubles inflammatoires tels que l'arthrite, de l'obésité, de l'ostéoporose et d'autres états similaires énumérés pouvant être traités avec des inhibiteurs de DPP IV.
Belyakov Sergei
Hamilton Gregory S.
Hurst David Chadwick
Kalish Vincent J.
Li Weixing
Guilford Pharmaceuticals Inc.
Mbm & Co.
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