Inhibitors of dna methyltransferase isoforms

Details Inhibitors of dna methyltransferase isoforms Inhibitors of dna methyltransferase isoforms

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2446606

This invention relates to the inhibition of DNA MeTase expression and enzymatic activity. The invention provides methods and agents for inhibiting specific DNA MeTase isoforms by inhibiting expression at the nucleic acid level or enzymatic activity at the protein level.

La présente invention concerne l'inhibition de l'expression de MeTase d'ADN et de l'activité enzymatique. La présente invention a pour objet des procédés et des agents permettant d'inhiber les isoformes de MeTase d'ADN spécifique en inhibant l'expression au niveau d'acide nucléique ou de l'activité enzymatique au niveau protéique.

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