Inhibitors of factor xa

Details Inhibitors of factor xa Inhibitors of factor xa

C - Chemistry, Metallurgy

07

C

C07C 311/16 (2006.01) A61K 31/18 (2006.01) A61K 31/33 (2006.01) A61P 7/02 (2006.01) C07C 311/46 (2006.01) C07D 213/40 (2006.01) C07D 217/22 (2006.01) C07D 295/192 (2006.01) C07D 295/26 (2006.01) C07D 307/52 (2006.01) C07D 333/20 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2374650

Compounds of the formula A - Y - D - E - G - J - Z - L in which D is a direct link, a substituted or unsubstituted phenyl or naphthyl group or a heterocyclic ring system and the other variables are as defined in the claims, their salts and other derivatives and compositions relating thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

La présente invention concerne des nouveaux composés, ainsi que leurs sels et leurs compositions, efficaces contre le facteur Xa mammalien. Ces composés sont utilisés in vitro et in vivo pour prévenir ou traiter les troubles de la coagulation.

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