C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/14 (2006.01) A61K 31/33 (2006.01) A61P 7/04 (2006.01) C07C 311/16 (2006.01) C07C 311/46 (2006.01) C07C 317/40 (2006.01) C07C 317/44 (2006.01) C07D 213/75 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 217/22 (2006.01) C07D 277/56 (2006.01) C07D 333/38 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 409/
Patent
CA 2385589
Compounds of formula A Q D E G J X in which D is a direct link, a substituted or unsubsituted phenyl or naphtyl gourp or a heterocyclic ring system; G is substituted or unsubstituted phenyl or a heterocyclic ring system; X is a substituted or unsubstituted phenyl or naphtyl group or a heterocyclic ring system; and the other variables are as defined in the claims, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed, The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
L'invention concerne de nouveaux composés, leurs sels et des compositions les contenant, efficaces contre le facteur Xa mammalien. Ces composés sont utilisés i<i>n vivo</i> et <i>in vitro</i> pour prévenir ou traiter les troubles de la coagulation.
Huang Wenrong
Jia Zhaozhong Jon
Kanter James
Scarborough Robert M.
Song Yonghong
Bereskin & Parr
Millennium Pharmaceuticals Inc.
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