C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 17/04 (2006.01) A61K 31/19 (2006.01) A61K 31/225 (2006.01) A61K 31/365 (2006.01) C07C 57/13 (2006.01) C07C 69/593 (2006.01) C07C 69/602 (2006.01) C07D 307/36 (2006.01) C12N 1/14 (2006.01) C12P 7/44 (2006.01)
Patent
CA 2084796
130/MRD83 18612 TITLE OF THE INVENTION INHIBITORS OF FARNESYL PROTEIN TRANSFERASE ABSTRACT OF THE INVENTION This invention relates to pharmaceutical compounds of structural formulae (I) and (II): Image (I) Image (II) and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.
Bills Gerald F.
Lingham Russell B.
Silverman Keith C.
Singh Sheo B.
Zink Deborah L.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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