C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/078 (2006.01) A61K 38/05 (2006.01) A61P 35/00 (2006.01) C07D 403/06 (2006.01)
Patent
CA 2681351
One aspect of the present invention relates to synthetic peptide derivatives that inhibit fibroblast activation protein .alpha. (FAP) activity. Another aspect of the invention relates to methods for treating a mammal suffering from cancer by administering a therapeutically effective amount of synthetic peptides derivatives that inhibit FAP activity.
Un aspect de l'invention concerne des dérivés peptidiques synthétiques qui inhibent l'activité .alpha. de la protéine d'activation des fibroblastes (PAF). Un autre aspect de l'invention concerne des méthodes de traitement d'un mammifère atteint du cancer par l'administration d'une dose thérapeutiquement efficace de dérivés peptidiques synthétiques qui inhibent l'activité .alpha. de la protéine d'activation des fibroblastes (PAF).
Bachovchin William W.
Lai Hung-Sen
Borden Ladner Gervais Llp
Trustees Of Tufts College
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