Inhibitors of gob-4 protein as asthma therapeutics

Details Inhibitors of gob-4 protein as asthma therapeutics Inhibitors of gob-4 protein as asthma therapeutics

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01)

Patent

CA 2560292

Methods of screening for agents for treating asthma are provided. The methods involve screening for agents that decrease the production or activity of a Gob- 4 protein that has been discovered herein to play a role in producing the symptoms and pathological complications involved in asthma. Methods of treating asthma, as well as screening for and treating with inhibitors of a Gob-4 protein are also provided.

L'invention porte sur des procédés de criblage d'agents de traitement de l'asthme consistant à rechercher des agents réduisant la production ou l'activité de la protéine Gob-4 dont l'invention a découvert le rôle joué dans la production des symptômes et des complications pathologiques liées à l'asthme. L'invention porte également sur des procédés de traitement de l'asthme, et de criblage d'inhibiteurs de la protéine Gob-4 et de traitements associés.

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