C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/14 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4439 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2680467
The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. One aspect of the invention provides compounds of formula (1): (1), in which T, A and X are as described herein.
L'invention concerne l'inhibition de l'histone désacétylase. L'invention concerne des composés et des procédés destinés à inhiber l'activité enzymatique de l'histone désacétylase. L'invention concerne également des compositions et des procédés pour traiter les maladies et les troubles associés à la prolifération cellulaire. Un aspect de l'invention concerne des composés de formule (1) : (1), dans laquelle T, A et X sont tels que décrits dans le présent document.
Frechette Sylvie
Isakovic Lubo
Moradei Oscar
Paquin Isabelle
Roy Simon
Mbm Intellectual Property Law Llp
Methylgene Inc.
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