Inhibitors of histone deacetylase

Details Inhibitors of histone deacetylase Inhibitors of histone deacetylase

C - Chemistry, Metallurgy

07

C

C07C 259/06 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 31/33 (2006.01) C07C 311/19 (2006.01) C07C 323/50 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2683557

This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula compounds of the Formula (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein groups L, M, X and Y are as defined herein.

L'invention concerne des composés permettant d'inhiber l'histone déacétylase. Plus particulièrement, l'invention concerne des composés représentés par la formule (I) et, N-oxydes, des hydrates, des solvates et des sels pharmaceutiquement acceptables, des promédicaments et des complexes de ces composés, ainsi que des mélanges racémiques et scalémiques, des diastéréomères et des énantiomères de ceux-ci, les groupes L, M, X et Y étant tels que définis dans la description.

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