Inhibitors of histone deacetylase and prodrugs thereof

Details Inhibitors of histone deacetylase and prodrugs thereof Inhibitors of histone deacetylase and prodrugs thereof

C - Chemistry, Metallurgy

07

C

C07C 259/04 (2006.01) A61K 31/10 (2006.01) A61K 31/16 (2006.01) A61K 31/17 (2006.01) A61K 31/18 (2006.01) A61K 31/34 (2006.01) A61K 31/381 (2006.01) A61P 31/10 (2006.01) A61P 35/00 (2006.01) C07C 259/10 (2006.01) C07C 275/42 (2006.01) C07C 311/21 (2006.01) C07C 317/44 (2006.01) C07D 307/54 (2006.01) C07D 333/34 (2006.01) C07D 333/62 (2006.01)

Patent

CA 2672192

The invention relates to the inhibition of histone deacetylase. The invention provides compounds, prodrugs thereof, and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.

L'invention porte sur l'inhibition de l'histone désacétylase. L'invention concerne des composés, des pro-médicaments de ceux-ci et des procédés pour inhiber l'activité enzymatique histone désacétylase. L'invention porte également sur des compositions et des procédés pour traiter des maladies et des états de prolifération cellulaire.

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