Inhibitors of hiv-1 reverse transcriptase

Details Inhibitors of hiv-1 reverse transcriptase Inhibitors of hiv-1 reverse transcriptase

C - Chemistry, Metallurgy

07

D

C07D 213/64 (2006.01) A61K 31/135 (2006.01) A61K 31/33 (2006.01) C07C 215/76 (2006.01) C07C 217/80 (2006.01) C07D 215/227 (2006.01) C07D 217/24 (2006.01) C07D 263/00 (2006.01) C07D 277/00 (2006.01) C07D 307/81 (2006.01) C07D 333/00 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2063909

TITLE OF THE INVENTION INHIBITORS OF HIV-1 REVERSE TRANSCRIPTASE ABSTRACT OF THE DISCLOSURE Novel aniline derivatives containing hydroxy and hydroxymethyl groups inhibit HIV-1 reverse transcriptase, and are useful in the prevention or treatment of infection by HIV-1 and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, anti-infectives, immunomodulators, antibiotic or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV-1 are also described.

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