Inhibitors of human immunodeficiency virus replication

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/04 (2006.01) A61K 31/4365 (2006.01) A61K 31/4709 (2006.01) A61K 31/4741 (2006.01) A61K 31/538 (2006.01) A61P 31/18 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2705312

The present invention relates to compounds of formula (I) wherein c, X, Y, R2, R3, R4 and R6 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HIV infection.

La présente invention concerne des composés de formule (I) dans laquelle c, X, Y, R2, R3, R4 et R6 sont tels que définis dans la description. Elle concerne des compositions et des utilisations desdits composés pour le traitement d'une infection par le virus de l'immunodéficience humaine (VIH). L'invention concerne en particulier de nouveaux inhibiteurs de l'intégrase du VIH, des compositions pharmaceutiques contenant ces composés, et des méthodes d'utilisation de ces composés dans le traitement d'une infection par le VIH.

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