C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/4745 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2654410
The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.
La présente invention concerne des composés qui inhibent les quatre kinases JAK mammaliennes (JAK1, JAK2, JAK3 et TYK2) bien connues et la kinase PDK1. L'invention concerne également des compositions contenant de tels composés inhibiteurs et des procédés permettant d'inhiber l'activité de JAK1, JAK2, JAK3 TYK2 et PDK1 par l'administration du composé à un patient qui nécessite des soins pour des troubles associés à une myéloprolifération ou un cancer.
Haidle Andrew
Machacek Michelle
Tempest Paul
Young Jonathan R.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
LandOfFree
Inhibitors of janus kinases does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibitors of janus kinases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of janus kinases will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1865341