Inhibitors of mammalian hdac 11 useful for treating hdac 11...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 31/713 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2553468

The present invention, relies, in part, on the discovery of the role of HDAC 11 in various cell proliferative disorders including cancer. In the main, the invention provides for methods of inhibiting HDAC 11 as a means of treating cell proliferative disorders. Reagents for use in inhibiting human HDAC 11 are also provided.

Cette invention concerne, en partie, la découverte du rôle de HDAC 11 dans divers troubles de prolifération cellulaire et notamment le cancer. Principalement, l'invention concerne des procédés permettant d'inhiber HDAC 11 en tant que moyens permettant de traiter de troubles de prolifération cellulaire. L'invention concerne également des réactifs destinés à être utilisés pour inhiber HDAC 11 humain.

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