C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/40 (2006.01) A61K 31/66 (2006.01) C07F 9/117 (2006.01) A61K 31/22 (2006.01) A61K 31/265 (2006.01) C07C 53/134 (2006.01) C07C 55/28 (2006.01) C07C 59/125 (2006.01) C07C 59/305 (2006.01) C07C 69/013 (2006.01) C07C 69/96 (2006.01)
Patent
CA 2335995
The present invention relates to the preparation and biological activity of 3- deoxy-D-myo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. The compounds of the present invention are useful as anti-tumor agents which effectively inhibit the growth of mammalian cells.
Préparation et activité biologique d'analogues lipides de 3-désoxy-D-myo-inositol éther en tant qu'inhibiteurs de la signalisation par la phosphatidylinositol-3-kinase et de la croissance cellulaire tumorale. Les composés selon la présente invention sont utiles en tant qu'agents anti-tumoraux qui inhibent efficacement la croissance de cellules de mammifères.
Kozikowski Alan P.
Powis Garth
Qiao Lixin
Arizona Board Of Regents On Behalf Of The University Of Arizona
Georgetown University School Of Medicine
Gowling Lafleur Henderson Llp
LandOfFree
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