Inhibitors of plasma kallikrein

Details Inhibitors of plasma kallikrein Inhibitors of plasma kallikrein

C - Chemistry, Metallurgy

07

D

C07D 231/14 (2006.01) A61K 31/34 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/4192 (2006.01) A61K 31/426 (2006.01) A61K 31/4427 (2006.01) A61P 9/10 (2006.01) C07D 207/34 (2006.01) C07D 209/42 (2006.01) C07D 249/04 (2006.01) C07D 277/56 (2006.01) C07D 307/68 (2006.01) C07D 307/85 (2006.01) C07D 333/38 (2006.01) C07D 333/68 (2006.01) C07D 401/06 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2658523

The present invention provides compounds that inhibit the activity of plasma kallikrein (PK) and methods of preventing and treating the formation of thrombin during or after a PK dependent disease or condition, for example, after fibrinolysis treatment.

L'invention concerne des composés inhibant l'activité de la kallicréine plasmatique (PK) et des procédés visant à prévenir et à traiter la formation de thrombine pendant une maladie ou un état dépendant de PK, ou après une telle maladie ou un tel état, par exemple après un traitement de fibrinolyse.

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