C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/14 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/551 (2006.01) C07D 223/08 (2006.01) C07D 233/54 (2006.01) C07D 241/04 (2006.01) C07D 295/04 (2006.01) C07D 401/06 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2363169
The present invention comprises piperazine-containing compounds which inhibit prenyl-protein transferases, including farnesyl-protein transferase and geranylgeranyl-protein transferase type I. Such therapeutic compounds are useful in the treatment of cancer.
La présente invention concerne des composés pipéraziniques inhibiteurs des prényle-protéine transférases, et notamment la farnésyle-protéine transférase et la géranylgéranyle-protéine transférase de type I. De tels composés thérapeutiques conviennent au traitement du cancer.
Bergman Jeffrey M.
Hartman George D.
Lumma William C. Jr.
Sisko John T.
Smith Anthony M.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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