Inhibitors of prenyl-protein transferase

Details Inhibitors of prenyl-protein transferase Inhibitors of prenyl-protein transferase

C - Chemistry, Metallurgy

07

D

C07D 403/14 (2006.01) A61K 31/496 (2006.01) A61K 31/551 (2006.01) A61P 13/12 (2006.01) A61P 27/02 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 233/54 (2006.01) C07D 241/08 (2006.01) C07D 243/08 (2006.01) C07D 295/04 (2006.01) C07D 295/06 (2006.01) C07D 295/084 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C12N 9/99 (2006.01)

Patent

CA 2362778

The present invention comprises piperazine-containing compounds which inhibit prenyl-protein transferases, including farnesyl-protein transferase and geranylgeranyl-protein transferase type I. Such therapeutic compounds are useful in the treatment of cancer.

L'invention concerne des composés contenant de la pipérazine, qui inhibent les prényle protéine transférases, y compris la farnésyle protéine transférase et la géranylgéranyle protéine transférase de type I. Ces composés thérapeutiques sont utiles dans le traitement du cancer.

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