Inhibitors of protein farnesyl transferase

Details Inhibitors of protein farnesyl transferase Inhibitors of protein farnesyl transferase

C - Chemistry, Metallurgy

07

K

C07K 5/078 (2006.01) A61K 38/05 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2253934

Novel inhibitors of protein farnesyl transferase enzymes are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in treating cancer, restenosis, psoriasis, endometriosis, atherosclerosis, or viral infections.

Cette invention concerne de nouveaux inhibiteurs d'enzymes du type farnésyltransférase de protéines, ainsi que des procédés de préparations de ces inhibiteurs et des compositions les contenant. Ces inhibiteurs sont utiles dans le traitement du cancer, de la resténose, du psoriasis, de l'endométriose, de l'athérosclérose ou, encore, d'infections virales.

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