Inhibitors of protein kinases

Details Inhibitors of protein kinases Inhibitors of protein kinases

C - Chemistry, Metallurgy

07

D

C07D 213/60 (2006.01) A61K 31/44 (2006.01) A61K 31/519 (2006.01) A61K 31/541 (2006.01) A61P 35/00 (2006.01) C07D 333/38 (2006.01) C07D 491/048 (2006.01)

Patent

CA 2635888

The present invention is directed to a compound having the formula (I) wherein R1, R2, R3, R4, G, and Q are defined herein. The compounds of the present invention are useful as inhibitors of protein kinases. The present invention is also directed to compositions comprising a compound according to the above formula. The present invention is also directed to compounds that stabilize the open conformation of a protein kinase, a crystallized protein kinase ih the open conformation, and uses thereof. The compounds and compositions described herein are useful for treating and preventing an inflammatory condition or disease.

La présente invention concerne un composé de formule (I) où R1, R2, R3, R4, G et Q sont tels que définis dans la description de l'invention. Les composés selon la présente invention peuvent être employés en tant qu'inhibiteurs de protéine kinases. La présente invention concerne également des compositions comprenant un composé répondant à la formule ci-dessus. La présente invention concerne en outre des composés qui stabilisent la conformation ouverte d'une protéine kinase, une protéine kinase cristallisée en conformation ouverte et leurs applications de ladite protéine kinase. Les composés et les compositions décrits dans la présente invention peuvent être employés dans le traitement prophylactique et thérapeutique d'un état pathologique inflammatoire ou d'une maladie inflammatoire.

Affiliated with

Also associated with

Rating

Inhibitors of protein kinases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibitors of protein kinases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of protein kinases will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1676174