A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/57 (2006.01) A01N 1/02 (2006.01) A61P 37/06 (2006.01)
Patent
CA 2654446
Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In particular, the present invention relates to compositions and methods for inhibition of graft rejection and promotion of graft survival. Thus, the invention relates to modulation of cellular activities, including graft rejection, promotion of graft survival, graft versus host rejection and conditions commonly associated with graft rejection. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease and inducers of other alpha1-antitrypsin activities.
Des modes de réalisation de la présente invention illustrent des procédés pour traiter et prévenir la transplantation et les effets secondaires associés à la transplantation. En particulier, la présente invention concerne des compositions et des procédés pour empêcher le rejet du greffon et promouvoir la survie du greffon. L'invention concerne ainsi la modulation d'activités cellulaires, y-compris le rejet de greffon, la promotion de la survie du greffon, la réaction immunitaire de rejet de greffe, et les états généralement associés au rejet du greffon. L'invention concerne plus particulièrement des composés inhibiteurs comprenant des inhibiteurs naturellement présent et des inhibiteurs fabriqué par l'homme de la sérine protéase et des inducteurs d'autres activités .alpha.1-antitrypsine.
Dinarello Charles A.
Lewis Eli C.
Shapiro Leland
Smart & Biggar
The Regents Of The University Of Colorado
LandOfFree
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