Inhibitors of serine proteases, particularly hepatitis c...

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 5/10 (2006.01) A61K 38/55 (2006.01) C07K 5/02 (2006.01) C07K 5/117 (2006.01) C07K 7/02 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2268391

The present invention relates to compounds, methods and pharmaceutical compositions for inhibiting proteases, particularly serine proteases, and more particularly HCV NS3 proteases. The compounds, and the compositions and methods that utilize them, can be used, either alone or in combination to inhibit viruses, particularly HCV virus.

La présente invention concerne des composés, des procédés et des compositions pharmaceutiques destinés à l'inhibition de protéases, notamment de sérines protéases, et plus particulièrement de NS3 protéases du VHC. On peut utiliser les composés, ainsi que les compositions et procédés afférents, seuls ou combinés pour inhiber des virus, notamment le virus de l'hépatite C.

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