Inhibitors of ste20-like kinase (slk) and methods of...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/10 (2006.01) A61K 31/00 (2006.01) A61K 31/7088 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) G01N 33/574 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2623357

The invention provides inhibitors of Ste20-like kinase (SLK inhibitors). The inhibitors may be employed to modulate proliferation of cells, including tumor and cancer cells. The inhibitors also may be employed to inhibit motility or migration of cells, including cancer and tumor cells.

L'invention concerne des inhibiteurs de kinase de type Ste20 (inhibiteurs SLK). Les inhibiteurs peuvent être utilisés pour moduler la prolifération des cellules, y compris des cellules tumorales et des cellules cancéreuses. Les inhibiteurs peuvent être également utilisés pour inhiber la motilité ou la migration des cellules, y compris des cellules cancéreuses et des cellules tumorales.

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