Inhibitors of testosterone 5.alpha.-reductase activity

A - Human Necessities – 61 – K

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A61K 31/58 (2006.01) C07J 73/00 (2006.01)

Patent

CA 2136304

Inhibitors of testosterone 5.alpha.-reductase activity, for example those of formula (I) wherein novel substituents are provided at the R4, R6, R7, R17.alpha. and/or R17.beta. positions are useful for the treatment of diseases whose progress is aided by activation of an- drogen receptors. e.g., prostate cancer, benign prostatic hyperplasia, acne, seborrhea, hirsutism, androgenic alopecia and the like.

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