C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/7088 (2006.01) A61P 25/00 (2006.01) C07K 14/71 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2555463
The present invention relates to the use of oligonucleotides for the preparation of a pharmaceutical composition for the prevention or treatment of a disease, wherein neurogenesis and/or neuroregeneration has a beneficial effect, in particular a disease like Morbus Alzheimer, Morbus Parkinson, Lewy Body Dementia,-Amyotrophic Lateral Sclerosis, Spinocerebellar Atrophies, Creutzfeldt Jakob Disease, Frontemporal Dementia, Morbus Pick, AIDS Dementia Complex, Vascular Dementia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Multisystem-Atrophy, Hallervorden Spatz Disease, Huntington~s disease, Stroke, Traumatic Brain and spinal cord Injury, Retinitis Pigmentosa, Macular Degeneration, Glaucoma, Cochlea Degeneration, Depression, Schizophrenia, Multiple Sclerosis, and developmental neurodegeneration.
La présente invention porte sur l'utilisation d'oligonucléotides dans la préparation d'une composition pharmaceutique permettant de prévenir ou traiter une maladie, la neurogenèse et/ou la neurodégénération ayant un effet bénéfique, en particulier sur la maladie de Morbus Alzheimer, Morbus Parkinson, la démence à corps de Lewy, la sclérose latérale amyotrophique, les atrophies spinocérébrales, la maladie de Creutzfeldt Jakob, la démence frontotemporale Morbus Pick, l'encéphalopathie au VIH-1, la démence vasculaire, la paralysie supranucléaire évolutive, la dégénération corticobasale, l'atrophie multisystémique, la maladie de Hallervorden Spatz, la maladie d'Huntington, l'accident vasculaire cérébral, le traumatisme crânien et le traumatisme médullaire, la rétinite pigmentaire, la dégénération maculaire, le glaucome, la dégénération cohcléaire, la dépression, la schizophrénie, la sclérose en plaques et la neurodégénération du développement.
Aigner Ludwig
Bogdahn Ulrich
Wachs Frank Peter
Winkler Juergen
Winner Beate
Algner Ludwig
Bogdahn Ulrich
Hicks & Associates
Regenion Gmbh
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