C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/63 (2006.01) A61K 31/165 (2006.01) A61K 31/381 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/4409 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 213/56 (2006.01) C07D 231/12 (2006.01) C07D 261/08 (2006.01) C07D 333/24 (2006.01)
Patent
CA 2594116
The present invention relates to compounds that are inhibitors of the 11-beta- hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
L'invention concerne des composés qui sont des inhibiteurs de l'enzyme 11-béta-hydroxystéroïde déhydrogénase de type 1. L'invention concerne en outre l'utilisation d'inhibiteurs de l'enzyme 11-béta-hydroxystéroïde déhydrogénase de type 1, pour le traitement de diabètes de type 2 non-insulinodépendant, de la résistance à l'insuline, de l'obésité, de troubles lipidiques, de syndrome métabolique et d'autres maladies et états qui sont occasionnés par une action glucocorticoïde excessive.
Dinges Jurgen
Kurukulasuriya Ravi
Link James T.
Patel Jyoti R.
Rohde Jeffrey J.
Abbott Laboratories
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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