C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 235/14 (2006.01) A61K 31/4402 (2006.01) A61P 3/10 (2006.01) C07C 317/16 (2006.01) C07C 323/41 (2006.01) C07D 207/48 (2006.01) C07D 213/64 (2006.01) C07D 233/54 (2006.01) C07D 257/04 (2006.01) C07D 261/08 (2006.01)
Patent
CA 2594098
The present invention relates to compounds which are inhibitors of the 11-beta- hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
La présente invention concerne des composés inhibiteurs de l'enzyme 11-bêta-hydroxystéroïde déshydrogénase de Type 1. La présente invention concerne en outre l'emploi d'inhibiteurs de l'enzyme 11-bêta-hydroxystéroïde déshydrogénase de Type 1 dans le traitement du diabète de type 2 non insulinodépendant, de l'insulinorésistance, de l'obésité, des troubles lipidiques, du syndrome métabolique et d'autres maladies et états pathologiques médiés par une suractivité des glucocorticoïdes.
Dinges Jurgen
Link James T.
Patel Jyoti R.
Rohde Jeffrey J.
Shuai Qi
Abbott Laboratories
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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