Inhibitors of the .alpha.2.beta.1/gpia-iia integrin

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01)

Patent

CA 2611319

Novel compounds inhibiting the integrin .alpha.2.beta.l/GPIa-IIa receptor are disclosed. Also disclosed are pharmaceutical compositions containing the compounds, as well as methods of their therapeutic use. The compounds disclosed are useful, inter alia, as inhibitors of integrin .alpha.2.beta.l/GPIa-IIa-mediated activity.

La présente invention a trait à de nouveaux composés inhibiteurs du récepteur de l'intégrine a2ßl/GPIa-IIa. L'invention a également trait à des compositions pharmaceutiques contenant les composés, ainsi qu'à leurs procédés d'utilisation thérapeutique. Les composés de l'invention sont utiles, entre autres, comme inhibiteurs de l'activité médiée par l'intégrine a2ßl/GPIa-IIa.

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