Inhibitors of the chemokine receptor cxcr3

Details Inhibitors of the chemokine receptor cxcr3 Inhibitors of the chemokine receptor cxcr3

C - Chemistry, Metallurgy

07

D

C07D 295/033 (2006.01) A61K 31/495 (2006.01) A61P 29/00 (2006.01) C07D 471/20 (2006.01)

Patent

CA 2715557

This invention is directed to a 3-(amido or sulphamido)-4-(4-substituted- azinyl)benzamide or benzsulphonamide compound as defined herein. The 3-(amido or sulphamido)-(4-substituted- azinyl)benzamide or benzsulphonamide compound is useful as a inhibitor of the chemokine receptor CxCR3, and for preventing or treating a CxCR3 chemokine receptor mediated disease or condition related thereto in a patient in need of such.

Cette invention concerne un composé 3-(amido ou sulfamido)-4-(4-azinyle substitué)benzamide ou benzsulfonamide défini ici. Le composé 3-(amido ou sulfamido)-(4-azinyle substitué)benzamide ou benzsulfonamide est utile comme inhibiteur du récepteur de chimiokine CXCR3, et pour la prévention ou le traitement d'une maladie médiée par le récepteur de chimiokine CXCR3 ou d'une affection associée chez un patient le nécessitant.

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