C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4045 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2699849
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds; wherein n, m, p, s, t, R1, R2, R3, R4, R, R6, R7, R20, X, Y, Q and Z have defined meanings.
La présente invention concerne des composés de formule (I), leur utilisation comme inhibiteur d'une interaction p53-MDM2, ainsi que des compositions pharmaceutiques comprenant ces composés. Dans ladite formule (I), n, m, p, s, t, R1, R2, R3, R4, R5, R6, R7, R20, X, Y, Q et Z ont des significations définies.
Coupa Sophie
Poncelet Virginie Sophie
Schoentjes Bruno
Storck Pierre-Henri
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica Nv
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