C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4409 (2006.01) A61P 35/00 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2644643
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, s, t, R1, R2, A and Z have defined meanings.
La présente invention concerne des composés répondant à la formule (I), leur utilisation en tant qu'inhibiteur d'une interaction p53-MDM2 aussi bien que des compositions pharmaceutiques incluant lesdits composés de formule (I), n, m, p, s, t, R1, R2, A et Z ayant des significations déterminées.
Lacrampe Jean Fernand Armand
Lardeau Delphine Yvonne Raymonde
Meyer Christophe
Poncelet Alain Philippe
Schoentjes Bruno
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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