Inhibitors of the task-1 and task-3 ion channel

Details Inhibitors of the task-1 and task-3 ion channel Inhibitors of the task-1 and task-3 ion channel

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 31/166 (2006.01) A61K 31/18 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/44 (2006.01) A61K 31/4402 (2006.01) A61K 31/4406 (2006.01) A61K 31/4418 (2006.01) A61K 31/444 (2006.01) A61K 31/47 (2006.01) A61P 11/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2650391

The invention relates to the use of Kv1.5 inhibitors for producing a medicament for the therapy or prophylaxis of respiratory disorders, sleep-related respiratory disorders, central and obstructive sleep apneas, upper airway reisistance syndrome, Cheyne-Stokes respiration, snoring, disrupted central respiratory drive, sudden child death, postoperative hypoxia and apnea, muscle-related respiratory disorders, respiratory disorders after long-term ventilation, respiratory disorders during adaptation in high mountains, acute and chronic lung disorders with hypoxia and hypercapnia, neurodegenerative disorders, dementia, Alzheimer's disease, Parkinson's disease, Huntington's disease, cancer disorders, breast cancer, lung cancer, colon cancer and prostate cancer.

Cette invention concerne l'utilisation d'inhibiteurs Kv1.5 pour produire un médicament servant à traiter ou à prévenir les troubles respiratoires, les troubles respiratoires liés au sommeil, les apnées centrale et obstructive du sommeil, le syndrome de résistance des voies aériennes supérieures, la respiration de Cheyne-Stokes, le ronflement, la pulsion respiratoire centrale perturbée, la mort subite de l'enfant, l'hypoxie et l'apnée postopératoires, les troubles respiratoires associés aux muscles, les troubles respiratoires résultant d'une ventilation prolongée, les troubles respiratoires pendant l'adaptation en haute montagne, les troubles pulmonaires chroniques et aigus avec hypoxie et hypercapnie, les troubles neurodégénératifs, la démence, la maladie d'Alzheimer, la maladie de Parkinson, la maladie de Huntington, les troubles cancéreux, le cancer du sein, le cancer du poumon, le cancer du côlon et le cancer de la prostate.

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