A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/557 (2006.01) A61K 31/558 (2006.01) A61K 31/559 (2006.01) A61P 7/00 (2006.01) A61P 7/02 (2006.01) A61P 7/12 (2006.01) A61P 9/00 (2006.01) A61P 9/12 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01)
Patent
CA 2427774
Methods and compositions employing as active ingredient hepoxilins and hepoxilin analogs are useful for inhibiting thromboxane formation and antagonising thromboxane activity. Methods and compositions employing these compounds provide treatment for thrombosis, cardiovascular disease (hypertension), diabetes mellitus, septic shock, eye disease associated with inflammation (eye diobetic neuropathy) and/or increased intraocular pressure (glaucoma) or prevent or reduce thromboxan-mediated platelet aggregation.
La présente invention concerne des procédés et des compositions utilisant en tant que principe actif des hépoxilines et des analogues d'hépoxiline qui sont utiles pour l'inhibition de la formation de la thromboxane et antagonistes de l'activité de la thromboxane. L'invention concerne également des procédés et des compositions utilisant ces composés pour le traitement de divers états pathologiques.
Pace-Asciak Cecil R.
Sim & Mcburney
The Hospital For Sick Children
LandOfFree
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