C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 14/00 (2006.01) C07K 14/78 (2006.01) C07K 16/28 (2006.01) C07K 17/08 (2006.01) C12N 15/12 (2006.01) G01N 33/53 (2006.01) C07K 14/71 (2006.01) C07K 19/00 (2006.01)
Patent
CA 2552435
The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
L'invention porte sur de nouveaux polypeptides de fixation du récepteur de type 2 du facteur de croissance endothélial vasculaire (VEGFR), et sur des méthodes d'utilisation desdits polypeptides pour inhiber les activités biologiques médiées par les facteurs de croissance endothélial vasculaire (VEGF). L'invention porte également sur diverses améliorations relatives aux polypeptides de fixation à un domaine unique.
Chen Yan
Getmanova Elena
Gokemeijer Jochem
Harris Al
Lim Ai Ching
Bristol-Myers Squibb Company
Compound Therapeutics Inc.
Mbm Intellectual Property Law Llp
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