Inhibitors of type 3 3.alpha.-hydroxysteroid dehydrogenase

Details Inhibitors of type 3 3.alpha.-hydroxysteroid dehydrogenase Inhibitors of type 3 3.alpha.-hydroxysteroid dehydrogenase

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 31/565 (2006.01) A61K 31/566 (2006.01) A61K 31/567 (2006.01) A61K 31/5685 (2006.01) A61K 31/585 (2006.01) A61K 45/06 (2006.01) A61P 5/26 (2006.01) A61P 17/08 (2006.01) A61P 17/10 (2006.01) A61P 17/14 (2006.01) A61P 35/00 (2006.01) C07J 21/00 (2006.01)

Patent

CA 2339368

Novel methods of treating and/or inhibiting development of prostatic cancer, benign prostatic hyperplasia, prostatitis, acne, seborrhea, hirsutism or androgenic alopecia utilize inhibitors of type 3 3.alpha.-hydroxysteroid dehydrogenase alone or in combination with other active pharmaceuticals such as inhibitors of type 5 17.beta.-hydroxysteroid dehydrogenase. Novel inhibitors and pharmaceutical products are also disclosed.

L'invention porte sur de nouveaux procédés de traitement et/ou inhibition du développement du cancer de la prostate, de l'hyperplasie prostatique bénigne, des prostatites, de l'acné, de la séborrhée, de l'hirsutisme ou de l'alopécie masculine à l'aide de 3.alpha.-hydroxystéroid-déshydrogénase de type 3 seule ou combinée à d'autres produits pharmaceutiques actifs tels que les inhibiteurs 17.beta.-hydroxystéroid-déshydrogénase de type 5. L'invention porte également sur de nouveaux inhibiteurs et produits pharmaceutiques.

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