Inhibitors of undecaprenyl pyrophosphate synthase

Details Inhibitors of undecaprenyl pyrophosphate synthase Inhibitors of undecaprenyl pyrophosphate synthase

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/435 (2006.01) A61K 31/4353 (2006.01) A61P 31/04 (2006.01) C07D 221/04 (2006.01) C07D 401/12 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2659605

The present invention relates to compounds that are selective and/or potent inhibitors of UPPS. In addition to compounds which inhibit UPPS, the invention also provides pharmaceutical compositions comprising these compounds and methods of using these compounds for treating bacterial disease, such as bacterial infection.

L'invention concerne des composés qui sont des inhibiteurs sélectifs et/ou puissants de l'undécaprényl pyrophosphate systhase (UPPS). Outre les composants qui inhibent l'UPPS, l'invention concerne des compositions pharmaceutiques comprenant ces composés ainsi que des procédés d'utilisation de ces composés dans le traitement de maladies bactériennes, telles qu'une infection bactérienne.

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