Inhibitors of viral replication

Details Inhibitors of viral replication Inhibitors of viral replication

C - Chemistry, Metallurgy

07

D

C07D 233/76 (2006.01) C07D 207/09 (2006.01) C07D 211/62 (2006.01) C07D 233/74 (2006.01) C07D 233/78 (2006.01) C07D 235/02 (2006.01) C07D 295/12 (2006.01) C07D 295/18 (2006.01) C07D 307/68 (2006.01) C07D 403/06 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 413/04 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2624166

The embodiments provide compounds of the general Formulas I-IV, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

Les modes de réalisation de l~invention concernent des composés de formules générales I-IV, ainsi que des compositions, y compris des compositions pharmaceutiques, qui comprennent un composé objet de l~invention. Les modes de réalisation concernent en outre des méthodes de traitement, y compris des méthodes pour traiter une infection virale d~hépatite C et des méthodes pour traiter une fibrose hépatique ; lesdites méthodes impliquent généralement l~administration d~une quantité efficace d'un composé ou d~une composition objet de l~invention à un individu qui en a besoin.

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