C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/64 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 14/745 (2006.01) C07K 14/755 (2006.01) C07K 16/36 (2006.01) C07K 16/40 (2006.01) C12N 5/12 (2006.01) C12Q 1/37 (2006.01) C12Q 1/56 (2006.01) G01N 33/86 (2006.01)
Patent
CA 2418411
A monoclonal antibody which inhibits the blood clotting factor VII-activating protease and its proenzyme and a blood clotting factor VII-activating protease, stabilized by the addition of said monoclonal antibody, and its proenzyme are described. A suitable monoclonal antibody is produced by hybridoma cell line DSM ACC 2533. The application of the inhibitory, monoclonal antibody in the stabilization of blood clotting preparations and in preparations for reducing the coagulability of the blood is disclosed.
Feussner Annette
Kannemaier Christian
Lang Wiegand
Muth-Naumann Gudrun
Nakazawa Fumie
Aventis Behring Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Csl Behring Gmbh
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