Injectable aqueous solution containing hydrogensulfite...

A - Human Necessities – 61 – K

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A61K 31/55 (2006.01) A61K 33/04 (2006.01)

Patent

CA 1222700

Abstract of the Disclosure An alkali metal hydrogensulfite or sulfite is effective for controlling a local injury such as inflam- mation and vein injury occurring on the injection of an antitumor benzodiazepine compound of the formula Image wherein R1 denotes hydrogen atom, or acyl, carbamyl, or alkoxycarbonyl group; R2 denotes hydrogen atom or acyl group; and R3 denotes sulfinic acid rest, SO2X, or sulfonic acid rest, SO3X, X meaning hydrogen, alkali metal or alkaline earth metal. An aqueous solution con- taining the both can be administered by injection.

447152

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