Injectable bio-compatible material and methods of use

Details Injectable bio-compatible material and methods of use Injectable bio-compatible material and methods of use

A - Human Necessities

61

L

A61L 27/24 (2006.01) A61K 38/39 (2006.01) A61L 27/50 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01)

Patent

CA 2402000

A bio-compatible material which has a microstructure that is amenable to infiltration by living cells and which can support substantial and extended occupation by such living cells. In an embodiment, the bio-compatible material comprises a biopolymer, such as collagen. In another embodiment of the invention, the bio-compatible material is injectable (i.e., it can be applied percutaneously or internally by way of injection through a syringe needle). In a particularly advantageous embodiment, a fibrous bio-compatible material comprises a linearly assembled biopolymer fiber, which is assembled from biopolymer fibrils whose axes are substantially parallel with the axis of said biopolymer fiber.

Ce matériau biocompatible possède une microstructure susceptible d'être infiltrée par des cellules vivantes et pouvant supporter une occupation importante et étendue par de telles cellules vivantes. Dans un mode de réalisation, ce matériau biocompatible comprend un biopolymère, tel que du collagène. Dans un autre mode de réalisation de l'invention, ce matériau biocompatible est injectable (c'est-à-dire que l'on peut l'appliquer par voie percutanée ou interne, par injection au moyen d'une aiguille de seringue). Dans une variante de réalisation particulièrement avantageuse, le matériau biocompatible fibreux comprend une fibre biopolymère assemblée linéairement, dont l'assemblage est effectué à partir de fibrilles biopolymères dont les axes sont sensiblement parallèles à l'axe de la fibre biopolymère.

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